Rajeshwari Sridhara Selected Research

Disease Progression

1/2021	FDA Approval Summary: Olaparib Monotherapy or in Combination with Bevacizumab for the Maintenance Treatment of Patients with Advanced Ovarian Cancer.
10/2020	FDA Approval Summary: Pembrolizumab plus Lenvatinib for Endometrial Carcinoma, a Collaborative International Review under Project Orbis.
1/2020	FDA Approval Summary: Palbociclib for Male Patients with Metastatic Breast Cancer.
1/2020	Immune Response Evaluation and Treatment with Immune Checkpoint Inhibitors Beyond Clinical Progression: Response Assessments for Cancer Immunotherapy.
1/2018	Patients with melanoma treated with an anti-PD-1 antibody beyond RECIST progression: a US Food and Drug Administration pooled analysis.
1/2018	Evaluation of Overall Response Rate and Progression-Free Survival as Potential Surrogate Endpoints for Overall Survival in Immunotherapy Trials.
1/2018	FDA analyses of survival in older adults with metastatic non-small cell lung cancer in controlled trials of PD-1/PD-L1 blocking antibodies.
11/2017	FDA Approval Summary: Daratumumab for Treatment of Multiple Myeloma After One Prior Therapy.
10/2017	FDA Approval Summary: Pembrolizumab for the Treatment of Patients with Unresectable or Metastatic Melanoma.
7/2017	U.S. FDA Approval Summary: Nivolumab for Treatment of Unresectable or Metastatic Melanoma Following Progression on Ipilimumab.

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Rajeshwari Sridhara Research Topics

Disease

28	Neoplasms (Cancer) 01/2021 - 01/2003
20	Disease Progression 01/2021 - 05/2006
19	Diarrhea 01/2020 - 01/2003
17	Breast Neoplasms (Breast Cancer) 11/2021 - 07/2003
16	Nausea 01/2020 - 01/2003
15	Neutropenia 01/2020 - 02/2005
13	Fatigue 01/2020 - 01/2012
13	Exanthema (Rash) 01/2018 - 01/2003
11	Thrombocytopenia (Thrombopenia) 01/2020 - 03/2005
10	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2018 - 01/2003
9	Vomiting 01/2020 - 01/2003
8	Melanoma (Melanoma, Malignant) 01/2021 - 10/2014
8	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 07/2003
7	Headache (Headaches) 01/2020 - 03/2005
7	Anemia 01/2020 - 06/2012
7	Constipation 01/2020 - 03/2005
6	Multiple Myeloma 11/2017 - 07/2003
5	Ovarian Neoplasms (Ovarian Cancer) 01/2021 - 10/2006
5	Arthralgia (Joint Pain) 01/2020 - 03/2005
5	Peripheral Nervous System Diseases (PNS Diseases) 01/2020 - 05/2006
4	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2022 - 01/2010
4	Neoplasm Metastasis (Metastasis) 01/2020 - 07/2003
4	Alopecia (Baldness) 01/2020 - 10/2014
4	Musculoskeletal Pain 01/2020 - 09/2014
4	Hypertension (High Blood Pressure) 01/2018 - 12/2006
4	Renal Cell Carcinoma (Grawitz Tumor) 01/2017 - 12/2006
4	Asthenia 10/2015 - 05/2006
3	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2019 - 09/2006
3	Leukopenia 01/2018 - 09/2008
3	Dyspnea (Shortness of Breath) 01/2018 - 09/2013
3	Infections 10/2016 - 06/2005
3	Fever (Fevers) 09/2013 - 03/2005
2	Triple Negative Breast Neoplasms 01/2020 - 07/2014
2	Hemorrhage 01/2020 - 01/2008
2	Pain (Aches) 11/2019 - 07/2003
2	Carcinoma (Carcinomatosis) 01/2019 - 10/2006
2	Lung Neoplasms (Lung Cancer) 12/2018 - 01/2016
2	Malignant Mesothelioma 11/2018 - 02/2005
2	Mucositis 01/2018 - 01/2010
2	Nasopharyngitis 01/2018 - 10/2015
2	Back Pain (Backache) 01/2018 - 10/2015
2	Abdominal Pain (Pain, Abdominal) 12/2017 - 10/2015
2	Dysgeusia (Parageusia) 12/2017 - 10/2015
2	Myalgia 10/2015 - 08/2005
2	Non-Muscle Invasive Bladder Neoplasms 01/2015 - 02/2014
2	Hypophosphatemia 01/2009 - 12/2006
2	Philadelphia Chromosome 09/2008 - 01/2008
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 09/2008 - 01/2008
2	Febrile Neutropenia 09/2008 - 06/2005

Drug/Important Bio-Agent (IBA)

24	Pharmaceutical PreparationsIBA 11/2020 - 07/2003
9	PlatinumIBA 01/2021 - 01/2003
7	Hormones (Hormone)IBA 11/2021 - 07/2014
6	Trastuzumab (Herceptin)FDA Link 01/2020 - 10/2008
5	ErbB Receptors (EGF Receptor)IBA 12/2019 - 08/2005
5	Docetaxel (Taxotere)FDA Link 01/2018 - 01/2003
5	Bortezomib (Velcade)FDA Link 11/2017 - 05/2006
5	TabletsIBA 10/2014 - 02/2004
4	Phosphotransferases (Kinase)IBA 01/2021 - 12/2006
4	pembrolizumabIBA 10/2020 - 01/2017
4	Letrozole (Femara)FDA LinkGeneric 01/2020 - 08/2005
4	taxaneIBA 01/2020 - 07/2008
4	NivolumabIBA 07/2017 - 01/2016
4	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2010 - 08/2005
3	Fulvestrant (Faslodex)FDA Link 11/2021 - 10/2016
3	Cyclin-Dependent Kinase 4IBA 11/2021 - 01/2018
3	Immune Checkpoint InhibitorsIBA 01/2021 - 08/2017
3	enzalutamideIBA 01/2020 - 11/2013
3	Aromatase InhibitorsIBA 01/2020 - 01/2018
3	AntibodiesIBA 01/2020 - 01/2018
3	palbociclibIBA 01/2020 - 11/2015
3	Dacarbazine (DIC)FDA LinkGeneric 01/2019 - 10/2014
3	Cisplatin (Platino)FDA LinkGeneric 01/2019 - 02/2005
3	Biomarkers (Surrogate Marker)IBA 01/2018 - 05/2014
3	Dexamethasone (Maxidex)FDA LinkGeneric 11/2017 - 05/2006
3	Capecitabine (Xeloda)FDA Link 09/2016 - 07/2008
3	Lipase (Acid Lipase)FDA Link 01/2009 - 12/2006
2	olaparibIBA 01/2021 - 10/2015
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2021 - 01/2018
2	Biological ProductsIBA 11/2020 - 02/2014
2	Transaminases (Aminotransferases)IBA 01/2020 - 09/2014
2	Estrogen ReceptorsIBA 01/2020 - 11/2015
2	Ado-Trastuzumab EmtansineIBA 01/2020 - 09/2014
2	atezolizumabIBA 01/2020 - 01/2019
2	Lenalidomide (CC 5013)FDA Link 11/2017 - 10/2008
2	IpilimumabIBA 10/2017 - 07/2017
2	Antineoplastic Agents (Antineoplastics)IBA 01/2016 - 07/2003
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2016 - 02/2005
2	Sorafenib (BAY 43-9006)FDA Link 01/2009 - 12/2006
2	AnthracyclinesIBA 10/2008 - 07/2008
2	Tyrosine Kinase InhibitorsIBA 10/2008 - 12/2007
2	Imatinib Mesylate (Gleevec)FDA Link 09/2008 - 01/2008
2	Pemetrexed (MTA)FDA Link 06/2005 - 02/2005
2	Gefitinib (Iressa)FDA Link 02/2004 - 01/2003

Therapy/Procedure

40	Therapeutics 11/2021 - 07/2003
26	Drug Therapy (Chemotherapy) 10/2022 - 01/2003
6	Immunotherapy 01/2020 - 01/2018
5	Castration 01/2020 - 11/2013
3	Neoadjuvant Therapy 01/2021 - 07/2014
3	Radiotherapy 05/2014 - 07/2003
2	Drug Tapering 01/2018 - 09/2005